Nitric oxide and hydrogen sulfide share regulatory functions in higher plant events
  • FRANCISCO J. CORPAS*, SALVADOR GONZÁLEZ-GORDO, MARTA RODRÍGUEZ-RUIZ, MARÍA A. MUÑOZ-VARGAS, JOSÉ M. PALMA
Group of Antioxidants, Free Radicals and Nitric Oxide in Biotechnology, Food and Agriculture, Department of Biochemistry, Cell and Molecular Biology of Plants, Estación Experimental del Zaidín (Spanish National Research Council, CSIC), Granada, 18008, Spain
* Address correspondence to: Francisco J. Corpas, javier.corpas@eez.csic.es
Received 29 April 2021; Accepted 01 June 2021 ; Published online 17 June 2021
Abstract
Nitric oxide (NO) and hydrogen sulfide (H2S) are two molecules that share signaling properties in plant and animal cells. NO and H2S originate two families of derived molecules designated reactive nitrogen and sulfur species (RNS and RSS, respectively). These molecules are responsible for certain protein regulatory processes through posttranslational modifications (PTMs), being the most remarkable S-nitrosation and persulfidation, which affect the thiol group of cysteine residues. NO and H2S can also exert regulatory functions due to their interaction through the iron present in proteins that contain heme groups or iron-sulfur clusters, as reported mainly in animal cells. However, the available information in plant cells is still very limited thus far. In higher plants, NO and H2S are involved in a myriad of physiological events from seed germination to fruit ripening, but also the mechanism of response to biotic and abiotic stress conditions. This viewpoint manuscript highlights the functional regulatory parallelism of these two molecules which also interact with the metabolism of reactive oxygen species (ROS) in plant cells.
Keywords
Ascorbate peroxidase, Hydrogen sulfide, Nitric oxide, Persulfidation, S-nitrosation, Signaling